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Tomorrow’s Radar is Locked: See Why (Nasdaq: ACON) Will Be On Our Screens Early



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Krypton Street Just Added Aclarion, Inc. (Nasdaq: ACON) To The Top Of

Tomorrow's Watchlist—For Tuesday, December 2, 2025

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Take A Look At (ACON) Before Tomorrow Morning…

December 1, 2025

Tomorrow's Radar is Locked | See Why (Nasdaq: ACON) Will Be On Our Screens Early

Dear Reader,

After watching today's biopharma profile push approximately 40% higher before the closing bell, we immediately shifted our attention to the next name lining up on our radar for tomorrow morning.

It's a story rooted in a challenge that stretches across the entire spine-care landscape. More than 635,000 Americans undergo spinal fusion surgery every year—yet nearly half walk away without lasting relief.

Not because surgeons lack skill, but because the true source of pain isn't always clear. In many cases, the disc responsible for the problem remains unidentified until long after the first incision is made.Aclarion, Inc. (Nasdaq: ACON) is aiming to change that dynamic.

Its Nociscan platform—an AI-powered, non-invasive diagnostic built on magnetic resonance spectroscopy—targets the core issue with a level of precision traditional imaging hasn't been able to deliver.

It's the emergence of this technology, and the scale of the problem it addresses, that puts (ACON) at the top of our watchlist tomorrow morning—Tuesday, December 2, 2025.

But keep in mind, (ACON) has less than 700K shares listed in its public float. When floats are this small, the potential exists for big moves if demand begins to shift.

And Ascendiant Capital Markets analyst Lucas Ward has set a $23 target on (ACON), which suggests over 250% upside potential from its recent $6.35 range.

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Keep reading to see why (ACON) just landed on our radar.

Game-Changing Technology in a Massive Healthcare Market

Aclarion, Inc. (Nasdaq: ACON) has positioned itself at the convergence of artificial intelligence and precision medicine with Nociscan—a non-invasive platform that uses magnetic resonance spectroscopy (MRS) to pinpoint exactly which intervertebral discs are generating chronic low back pain.

This technology is supported by a deep intellectual property foundation, including 24 issued U.S. patents, 17 international patents, and an exclusive worldwide UCSF license covering disc biomarker identification. This creates meaningful barriers to competition as advanced diagnostic solutions continue shifting toward objective chemical analysis.

The market potential is staggering.

Low back and neck pain costs the U.S. healthcare system $135B annually, with 266M patients worldwide suffering from degenerative spine disease and chronic pain. In the United States alone, 16M people experience chronic low back pain each year.

Traditional MRI scans can reveal structural damage but cannot identify which specific disc is causing pain. Provocative discography—the current diagnostic standard—is invasive, intensely painful for patients, and relies on subjective patient feedback during the procedure.

Aclarion's (Nasdaq: ACON) Nociscan platform transforms this paradigm. By measuring chemical biomarkers including acidic pain markers—lactic acid, alanine, and propionate—the technology delivers objective, disc-by-disc analysis at half the cost of discography with zero invasiveness.

Clinical validation is already emerging. The Gornet study published in European Spine Journal demonstrated that 97% of patients improved when all Nociscan-positive discs were treated, versus only 54% improvement when a Nociscan-positive disc was left untreated. These results remained durable at 2-year follow-up data.

Commercial Traction Accelerating Across Key Markets

While Aclarion, Inc. (Nasdaq: ACON) remains in early-stage commercialization, momentum is building in ways that could significantly accelerate adoption curves.

The company has secured coverage from three of the top four private medical insurers in the United Kingdom—representing approximately 5.2M covered lives. Private payment and insurance comprise 72% of UK private hospital revenue, and The London Clinic is now executing a comprehensive commercial launch strategy to drive physician adoption.

In the U.S. market, Aclarion (Nasdaq: ACON) has established Category III CPT codes through the American Medical Association, creating the foundation for future reimbursement pathways. The company is actively engaging key opinion leaders at premier institutions including Johns Hopkins, UCSF, and Northwestern.

The data confirms accelerating traction: Q3 2025 Nociscan scan volumes surged 89% year-over-year, according to Ascendiant Capital Markets analyst Lucas Ward. While Q3 revenue of $18,942 remains modest in absolute terms, the growth trajectory indicates expanding clinical adoption as coverage decisions and validation studies progress.

The CLARITY Trial: A Pivotal Near-Term Catalyst

The most significant near-term value driver for Aclarion, Inc. (Nasdaq: ACON) is the CLARITY pivotal trial—a randomized, controlled, multi-site study comparing surgical outcomes when physicians have Nociscan data versus standard care without it.

Dr. Nicholas Theodore, Director of the Neurosurgical Spine Center at Johns Hopkins Medicine, serves as Principal Investigator. The study enrolled its first patient in June 2025 at UHealth - University of Miami, and Aclarion (Nasdaq: ACON) anticipates initial interim results in Q2 2026.

Eight sites are now qualified for the 300-patient study, which is fully funded at approximately $4.6M in total costs. If results validate Nociscan's clinical utility in improving surgical outcomes, this data could be transformative for broader payer coverage decisions.

The evidence pipeline extends beyond CLARITY. Aclarion (Nasdaq: ACON) currently has seven ongoing clinical trials and eight peer-reviewed publications, with over 250 patients studied to date across its clinical program.

Exceptional Financial Position Relative to Valuation

Perhaps the most compelling aspect of Aclarion, Inc. (Nasdaq: ACON) from a risk-reward perspective is the company's financial strength relative to current market capitalization.

As of October 14, 2025, Aclarion (Nasdaq: ACON) held $13.3M in cash—representing $15.11 per share on a fully diluted basis. The company subsequently raised approximately $2M in net proceeds via a registered direct offering in October 2025. With projected annual burn of $7-8M, Lucas Ward at Ascendiant calculates a cash runway extending well into 2027.

The capital structure is remarkably clean: zero debt, no preferred shares, and no near-term warrant overhang. The company maintains full Nasdaq compliance, meeting both minimum bid price and shareholder equity requirements.

With current market capitalization in the $4–6M range and net cash value estimated at roughly $17 per share, Ascendiant's analysis suggests that Aclarion is effectively hovering at levels that resemble a call option on the ongoing commercialization of Nociscan.

Technical Picture

Recent momentum demonstrates the volatility characteristic of smaller cap healthcare names. Aclarion, Inc. (Nasdaq: ACON) showcased an approximate 17% move in just two days, advancing from $5.55 on November 26 to $6.50 on November 28.

Technical indicators show RSI readings around 58-60, which some would consider to be a bullish indicator.

The float deserves particular attention. With less than 700K shares available in the public float according to Yahoo Finance, (Nasdaq: ACON)'s limited share availability could result in outsized moves if buying interest materializes.

7 Reasons (Nasdaq: ACON) Will Be the First Name We Pull Up

Tuesday Morning—December 2, 2025.

1. Extremely Limited Float: With less than 700K shares in the public float per Yahoo data, (Nasdaq: ACON) has the type of limited share availability that can lead to significant price moves when demand shifts.

2. Analyst Target: Ascendiant Capital Markets analyst Lucas Ward maintains a $23 target on (Nasdaq: ACON), which suggests over 250% upside potential from recent levels.

3. Trending Below Net Cash Value: At $13.3M cash on hand against a $4-6M market cap, Aclarion (Nasdaq: ACON) offers more than $17 per share in net cash while still well below that threshold—an unusual value proposition.

4. Clear Clinical Catalyst Timeline: CLARITY trial interim results expected Q2 2026 provide a defined milestone that could validate Aclarion's (Nasdaq: ACON) clinical thesis and potentially accelerate payer adoption decisions.

5. Commercial Momentum Gaining Speed: Q3 scan volumes up 89% year-over-year, combined with UK private insurance coverage from three top-tier payers, demonstrates that sophisticated healthcare organizations see value in the technology.

6. Robust Intellectual Property Protection: 24 issued U.S. patents and 17 issued international patents, including an exclusive worldwide UCSF license for disc biomarkers, create meaningful barriers to competition around Aclarion's (Nasdaq: ACON) core platform.

7. Addressing Healthcare's Largest Cost Center: The $135B U.S. market for low back and neck pain represents one of healthcare's most significant expense categories, with 266M patients suffering globally—providing substantial long-term expansion potential.

Take A Look At (ACON) Before Tomorrow Morning…

Aclarion, Inc. (Nasdaq: ACON) presents an exciting setup for those focused on transformative healthcare technologies trading at significant discounts to intrinsic value. The company combines breakthrough diagnostic technology addressing a massive market, accelerating commercial adoption, and adequate capital to reach pivotal milestones—all while trading below net cash value.

With an analyst projecting over 250% upside, an extremely limited float that could witness the potential for big swings and clinical catalysts approaching, (ACON) warrants very close attention right now.

We'll be looking at (ACON) right out of the gate tomorrow.

Expect a follow-up alert that could hit early, so be ready.

Have a good night.

Alex Ramsay

Co-Founder / Managing Editor

Krypton Street Newsletter

 

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