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Low Float (Nasdaq: ACON) Shoots Green Early Thursday (Breaking News Takes The Spotlight)



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Low Float (Nasdaq: ACON) Shoots Green Early Thursday (Breaking News Takes The Spotlight)


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December 4th

Greetings Readers,


Aclarion, Inc. (Nasdaq: ACON) is making an early green statement Thursday.


This comes on the heels of breaking news this morning. Check it out:


Aclarion Announces Publication of Nociscan Article in Special Pain Issue of the International Journal of Spine Surgery (IJSS)


Featured article strengthens growing body of clinical evidence for Nociscan by highlighting a successful case study


Special Pain issue features breakthrough innovations shaping the future of spine care


IJSS publishes over 150 articles annually representing 40+ nations


BROOMFIELD, Colo., Dec. 04, 2025 (GLOBE NEWSWIRE) -- Aclarion, Inc., (“Aclarion” or the “Company”) (Nasdaq: ACON, ACONW), a heal-thcare technology company that is leveraging biomarkers and proprietary augmented intelligence (AI) algorithms to help physicians identify the location of chronic low back pain, announced today the publication of a featured article Tech Update, sponsored by Aclarion, in the upcoming Special Pain Issue of the International Journal of Spine Surgery (IJSS).


The Special Pain Issue of IJSS highlights a simple truth: pain is not just a symptom—it is a complex neurobiological, psychological, and existential condition,said Morgan P. Lorio, MD, FACS, Guest Editor.As more granular diagnostics and increasingly granular ICD-10 classifications emerge—including pre-MRS tools capable of identifying the pain generator—clinicians are gaining new ways to ‘see’ pain that were previously inaccessible. This edition brings together innovations that integrate objective biomarkers with clinical judgment and ultimately improve how we diagnose, treat, and prevent suffering. IJSS is publishing this issue now because the field is at an inflection point, and our patients deserve nothing less than a more complete, science-driven understanding of pain.


Aclarion’s Nociscan solution is the first evidence-supported SaaS platform to noninvasively help physicians distinguish between painful and nonpainful discs in the lumbar spine for the estimated 266 million people who suffer from chronic low back pain worldwide.


In the case example highlighted, a 27-year-old patient with chronic low back pain initially underwent an MRI of the lumbar spine which visually suggested the L4/5 and L5/S1 disc levels were likely the source of this patient’s pain. The treating surgeon subsequently ordered a four-level Nociscan exam to gather more information. Nociscan revealed pain biomarkers for the L5/S1 disc but not for the L4/5 disc. The surgeon utilized this information in conjunction with the MRI data and the patient’s overall clinical history to limit the surgical intervention to an artificial disc replacement at only the L5/S1 disc resulting in the elimination of the patient’s pain and full return to an active lifestyle.


We are pleased that the Nociscan Tech Update is featured in the Special Pain Issue of such a high caliber journal like IJSS,said Ryan Bond, Chief Strategy Officer at Aclarion.The journal has long been a leader among its peers for advancing scientific and clinical excellence in spine care. The Special Pain Issue is emblematic of its commitment to enhancing the science and practice of non-operative and surgical interventions to restore and improve function to the spine. Likewise, at Aclarion, we are dedicated to giving physicians new insights extracted from MR Spectroscopy (MRS) to better understand a patient’s pain and differentiate between pathological pain and physiological aging.


...


Read the full article here.


Pair this news with a low float of fewer than 1Mn shares according to Yahoo Finance, and ACON could witness some seriously heightened volatility.


Spend a second reviewing my initial (Nasdaq: ACON) report below and consider this profile for your watchlist.

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A hands-on, tech-enabled approach is accelerating market adoption in a high-need heal-thcare segment.


This team blends biomarker insights with advanced AI to help clinicians locate disc-related pain and plan interventions more precisely.


Recent milestones include a debt-free balance sheet, ample cash runway, and record utilization of a next-generation imaging/diagnostic platform across major markets.


Their CLARITY trial is advancing on schedule, with early readouts anticipated in mid-2026, underscoring tangible progress toward smarter, data-driven surgical decisions.


If streamlined data and validated biomarkers could reshape patient outcomes, Wall Street may start paying close attention to what's shaping up here.


And with a tiny float under 1Mn shares, a massive analyst target suggesting triple-digit potential upside, and lots of strong news in the recent term, this under-the-radar Nasdaq profile is now topping my watchlist:


*Aclarion, Inc. (Nasdaq: ACON)*


Aclarion is a heal-thcare technology company focused on advancing the care of patients by combining the imaging capabilities of magnetic resonance spectroscopy (MRS) with a proprietary, augmented-intelligence algorithm to noninvasively deliver SaaS solutions that help physicians personalize treatment plans to support improved clinical outcomes and return patients to full, pain-free lives.


The company’s first solution will aim to address unmet needs in the low back and neck pain market.


And based on multiple potential catalysts, (Nasdaq: ACON) has quickly risen to the top of my watchlist. Check them out:


#1. A Very Small Float Could Create An Environment Ripe For Volatility.


#2. A Major Analyst $23 Target Suggests Triple-Digit Potential Upside.


#3. A Key Corporate Update Hints At Key Catalyst Potential Growing On The Horizon.


#4. The Company Earns An "Incredible Honor" As They're Named A "Rising Star."


#5. Two Recent Appointments Hope To Drive Commercial Efforts And Market Expansion.


But more on those in a second...


Where’s The Pain?


  • 266 Million patients worldwide suffer from degenerative spine disease and low back pain.(1)


  • Conventional imaging and diagnostics provide valuable structural information but struggle to identify the source of the pathogenic pain.


  • Low surgical success rates (41-57%)(2),(3) especially for patients suffering from Discogenic Chronic Low Back Pain (DCLP).


  • Of all the disease states, low back and neck pain account for the highest heal-thcare spending in U.S.(1)


One Simple NociScan = Volumes of Personalized Biomarker Data


Backed by Clinical Evidence


Based on methods validated by clinical studies, Aclarion’s proprietary signal processing software and expert system transforms raw spectral MRS data into clear metabolic biomarkers to help physicians determine between painful and nonpainful discs of the lumbar spine.


How it Works


In a conventional MRI, a simple, non-invasive MRS scan gathers raw spectral data on the chemical composition of the lumbar discs.


This raw data is sent to the Aclarion cloud based on methods validated by clinical studies.(1)


Aclarion’s proprietary signal processing software and expert system clarifies the signal and transforms the raw data into clear metabolic biomarkers for each disc.

Using augmented intelligence in a proprietary, post-processing algorithm, the Aclarion solution analyzes and quantifies the biomarker data, generating ratio metrics for each lumbar disc that are individualized to a normative data set.

Resulting in a simple, streamlined report that efficiently communicates individualized biomarker data for physician interpretation…


So physicians can make critical care decisions, in conjunction with standard practice, about the source of a patient's CLBP and the associated treatment strategy.


Key Takeaways

Grab Sources And More Here: ACON Website. ACON Presentation.

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And as I mentioned above, (Nasdaq: ACON) has multiple potential catalysts of focus. Take a look:


#1. ACON Potential Catalyst - A Very Small Float Could Create An Environment Ripe For Volatility.


According to the Yahoo Finance website, ACON has a tiny low float.


In fact, the website reports this profile to have approximately 671.34k shares in its float.


Why is that important? It's important on one crucial level. Volatility potential.


Could even more positive company news towards the end of 2025 provide a breakout spark when paired with this volatility potential?

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#2. ACON Potential Catalyst - A Major Analyst $23 Target Suggests Triple-Digit Potential Upside.


Last month, Ascendiant Capital Markets' analyst Lucas Warn released an update note on Aclarion, Inc. (Nasdaq: ACON) with a $23.00 price target.


From Wednesday's closing valuation, that target provides ACON with a potential upside of over 225%!


Here are some highlights from the report:


Raising 12-month price target to $23.00 (from $22.00): We are raising our 12- month target to $23.00 (from $22), based on a NPV analysis. Our new target of $23.00 represents 2.7x upside from the current share price. With net cash per share of $17, the st-ock resembles a call on the commercialization of Nociscan, a process which is well underway. Risks to our thesis include slower than expected traction with surgeons and higher than expected marketing and administrative expenses.

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#3. ACON Potential Catalyst - A Key Corporate Update Hints At Key Catalyst Potential Growing On The Horizon.


Aclarion Provides Corporate Update Highlighting Market Expansion as CLARITY Trial Advances Toward Key Data Catalyst


  • Debt-free balance sheet with $13.3Mn in cash... providing strategic flexibility for continued commercial growth


  • Nociscan scan volumes increase +89% year-over-year with third consecutive quarter of record utilization across U.S., U.K., and E.U. markets


  • CLARITY pivotal trial progressing on schedule and early 3-month readouts expected Q2 2026 as AI-driven disc pain biomarker validation continues


...


BROOMFIELD, Colo., Oct. 14, 2025 (GLOBE NEWSWIRE) -- Aclarion, Inc., (“Aclarion” or the “Company”) (Nasdaq: ACON, ACONW), a commercial-stage heal-thcare technology company that is leveraging biomarkers and proprietary augmented intelligence (AI) algorithms to help physicians identify the location of chronic low back pain, today issued its Q3 2025 corporate update highlighting its strong financial position, accelerating market adoption, and continued progress in the pivotal CLARITY trial.


Market Adoption & Growth Momentum


Nociscan scan volumes increased +89% year-over-year in Q3 – marking the third consecutive quarter of accelerating growth across U.S., U.K., and E.U. sites.


Three straight quarters of record utilization underscore growing physician adoption and commercial traction.


MR Spectroscopy and biomarker technology featured at the International Society of Pain and Neuroscience (ISPN) annual meeting in London validating the importance of disc chemistry as a key biomarker for chronic low back pain diagnosis.


...


Commercial expansion strategy on track to drive new revenue channels and strengthen global brand visibility in 2026.


Key Value Catalyst: CLARITY Trial Progress & AI Algorithm Validation


CLARITY pivotal trial advancing on schedule – first patients enrolled at UHealth-University of Miami Health System and the Miller School of Medicine, advancing progression towards full enrollment of CLARITY patients by Q4 2026.


Trial designed to quantify the clinical value of integrating Nociscan data into surgical planning, targeting outcomes that significantly exceed current ~54% industry benchmarks.


...


We are executing on our key milestones– expanding adoption, accelerating Nociscan growth, and advancing the CLARITY trial on time,said Brent Ness, Chief Executive Officer of Aclarion.Greg’s addition as CFO strengthens our leadership team at a pivotal inflection point. With a debt-free balance sheet, expanding data pipeline, and growing commercial traction, Aclarion is positioned to create meaningful long-term value for patients and shareholders alike.


...


Read the full article here.

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#4. ACON Potential Catalyst - The Company Earns An "Incredible Honor" As They're Named A "Rising Star."


Aclarion Wi-ns “Rising Star” at 2025 Digital Heal-th Hub Foundation: Digital Heal-th A-wards at HLTH


Company previously announced it was selected as a finalist from more than 1,800 submissions


A-ward w-i-n underscores growing impact of Aclarion’s breakthrough Nociscan solution for chronic low back pain


BROOMFIELD, Colo., Oct. 22, 2025 (GLOBE NEWSWIRE) -- Aclarion, Inc., (“Aclarion” or the “Company”) (Nasdaq: ACON, ACONW), a heal-thcare technology company that is leveraging biomarkers and proprietary augmented intelligence (AI) algorithms to help physicians identify the location of chronic low back pain, today announced it was named a Rising Star in the Clinical Diagnostic Device category during the 2025 Digital Health Hub Foundation: Digital Heal-th A-wards at HLTH.


Rising Star


The Digital Health A-wards are held annually and celebrates advancements in the digital heal-th industry. The Rising Star track highlights emerging digital heal-th companies that show exceptional potential and clinical impact. Chief Strategy Officer Ryan Bond accepted the a-ward on behalf of Aclarion, recognizing the company as a next-generation innovator making significant changes through technology for patients with chronic low back pain.


It’s an incredible honor to be recognized as a Rising Star and to be part of the Digital Health Awards at HLTH ecosystem that is shaping the future of digital heal-th,said Ryan Bond, Chief Strategy Officer of Aclarion.This a-ward underscores our team’s commitment to advancing objective, noninvasive information that helps physicians ‘see pain’ and make better treatment decisions for the millions suffering from chronic low back pain worldwide.


...


Read the full article here.

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#5. ACON Potential Catalyst - Two Recent Appointments Hope To Drive Commercial Efforts And Market Expansion.


Over the last month, ACON has made two key appointments:


12/2/25: Aclarion Appoints Jason Brosniak as Commercial Director to Drive Adoption and Market Expansion in the Eastern U.S.


11/5/25: Aclarion Appoints Dan Isherwood as UK Commercial Director to Drive Adoption and Market Expansion


Could these actions lead (Nasdaq: ACON) to strengthen their commercial execution and market growth?

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(Nasdaq: ACON) Recap - These 5 Potential Catalysts Are On Watch


#1. A Very Small Float Could Create An Environment Ripe For Volatility.


#2. A Major Analyst $23 Target Suggests Triple-Digit Potential Upside.


#3. A Key Corporate Update Hints At Key Catalyst Potential Growing On The Horizon.


#4. The Company Earns An "Incredible Honor" As They're Named A "Rising Star."


#5. Two Recent Appointments Hope To Drive Commercial Efforts And Market Expansion.

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Now officially underway: coverage is kicked-off on Aclarion, Inc. (Nasdaq: ACON).


Be on the lookout for updates coming out soon. Talk shortly.


Sincerely,

Kai Parker

StockWireNews


Sources: (1) Ravindra VM, Global Spine Journal (2018) 8(8): 784-794

(2) Wei J, Song Y, et al. Comparison of artificial total disc replacement versus fusion for lumbar disc disease: a meta-analysis of randomized controlled trials. Int Orthop. 2013; 37(7):1315-1325

(3) Ibrahim T, Tieyjeh IM, et al. Surgical versus nonsurgical treatment of chronic low back pain: a meta-analysis of randomized trials. Int Orthop. 2008; 32(1):107-113


(Always Remember The St-ock Prices Could Be Significantly Lower Now From The Dates I Provided.)


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